The Gunners are set to face Ludogorets for the second time in a fortnight after the 6-0 victory which saw Mesut Ozil record the first hat-trick of his career.
Arsene Wenger is without at least three key players as Hector Bellerin, Theo Walcott and Santi Cazorla sit out the trip to Bulgaria.
The trio will join Per Mertesacker and Danny Welbeck on the sidelines for now but their absence means a couple of fringe players have been given a chance to impress.
David Ospina, Carl Jenkinson, Granit Xhaka, Olivier Giroud and a fit-again Aaron Ramsey represent the changes Wenger has made to the team which began the match on Saturday.
Below is the Arsenal starting eleven to play Ludogorets…